self-destruction       
noun [ U ] uk/ˌself.dɪˈstrʌk.ʃən/ us/ˌself.dɪˈstrʌk.ʃən/
 自我毁灭
behaviour by a person that is likely to make them fail or cause them to be harmed or killed
  He was a wonderful actor bent on self-destruction. 他是一位优秀的演员,却自我毁灭的倾向非常明显。 
 See: self-destruct
 - More examples
 - What you also grasp is his stupendous gift for self-destruction.
 - Her loving family can only watch in horror at her self-destruction .
 - Others dismiss it as a wrongheaded notion that enables addicts to continue along the path to self-destruction.
 - And he commits what turns out to be an act of self-destruction.
 - That paranoia started his presidency down the path to self-destruction.