significance  
noun [ U ] uk/sɪɡˈnɪf.ɪ.kəns/ us/sɪɡˈnɪf.ə.kəns/
  (IMPORTANCE)      
 C1 重要性,重要意义
importance
  The discovery of the new drug is of great significance for/to people suffering from heart problems. 这种新药的发现对心脏病患者来说具有重要意义。 
 - More examples
 - They were offered a few cosmetic improvements to their working conditions, but nothing of significance.
 - And what might be the underlying significance of these supposedly random acts of violence?
 - His work is of great significance to historians.
 - We should not overestimate the significance of his influence.
 
  (SPECIAL MEANING)      
 特别意义,特殊含义
special meaning
  Do you think that look he gave you had any significance? 你觉得他看你的那一眼有什么特殊含义吗?