meltdown  
noun [ C or U ] uk/ˈmelt.daʊn/ us/ˈmelt.daʊn/
  (NUCLEAR)     
  (核电站核燃料的)熔毁
an extremely dangerous situation in a nuclear power station in which the nuclear fuel becomes very hot and melts through its container and escapes into the environment
   (FAILURE)        
 (尤指金融方面的)灾难
a complete failure, especially in financial matters
  financial/economic/market meltdown 金融/经济/市场崩溃 
 The last few months have seen the progressive meltdown of the country's political system. 过去几个月里,该国的政治体系一步步走向瓦解。 
  informal崩溃(指一个人极度悲伤而不能应对生活) 
an occasion when a person becomes extremely upset and is not able to deal with a problem or situation