get-go       
noun [ S ]  informal uk/ˈɡetˌɡəʊ/ us/ˈɡetˌɡoʊ/
 开始,开端
the beginning, when someone starts to do something, or a process starts
  The latest research shows that babies can be taught the difference between night and day from the get-go. 最新研究表明从一开始就可以教宝宝白天和晚上的不同。 
 Synonyms: beginningcommencementfirst start the outset