despairingly       
adverb uk/dɪˈspeə.rɪŋ.li/ us/dɪˈsper.ɪŋ.li/
 绝望地;失去希望地
showing that you feel that there is no hope and that you can do nothing to improve a difficult or worrying situation
  He rubbed his hand despairingly over his face. 他绝望地用手揉着脸。 
 "Now what?" she thought despairingly. 现在怎么办?她绝望地想。 
 See: despair
 - More examples
- He gazed despairingly about the room.
- She shook her head despairingly.
- He sighed despairingly.