lifework       
noun [ U ] US (also life work) uk/laɪfˈwɜːk/ us/laɪfˈwɝːk/
 倾注毕生心血的工作;毕生事业
Your lifework is the work that is most important to you and to which you give a lot of time and effort.
  Her garden was her lifework. 她对自己的花园倾注了极大的心血。 
 The environmentalist was honored for her life work in a special ceremony.
 Synonym: life's work
 - More examples
 - What influences led to your choice of acting as your lifework?
 - This cave is the centerpiece of the couple's lifework to save cave ecosystems in the region.
 - As a leading force for civil rights and civil liberties, and expander of democracy, his lifework will inspire political activitists for a long time.