screw (something) up 
phrasal verb with screw verb uk/skruː/ us/skruː/
  informal      
 犯错;搞糟;弄坏
to make a mistake, or to spoil something
  I totally screwed up the chemistry exam. 化学考试被我彻底考砸了。 
 Just don't screw up this time. 这次可别搞砸了。 
 
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