derail  
verb uk/ˌdiːˈreɪl/ us/ˌdiːˈreɪl/
  (TRAIN)     
  [ I or T ](使)(火车)脱轨 
If a train derails or is derailed, it comes off the railway tracks.
   (PLAN)      
 [ T ]阻挠 
to prevent a plan or process from succeeding
  Renewed fighting threatens to derail the peace talks. 重燃的战火对和谈构成了威胁。