estrangement          
noun  formal uk/ɪˈstreɪndʒ.mənt/ us/ɪˈstreɪndʒ.mənt/
 [ C or U ]疏远;疏远期 
a period when you are estranged from someone (= no longer friendly with them), or the fact of no longer being friendly
  Their reunion followed a long estrangement. 他们的重逢发生在长期的疏远之后。 
 He talked about his estrangement from his family.  他谈到了他与家人的疏远。 
  [ U ]隔阂;疏远 
a feeling that you do not understand someone or something, or do not have any connection with him, her, or it
  College athletes share a feeling of estrangement from the other students. 大学运动员与其他学生有一种隔阂的感觉。 
 See: estranged
 - More examples
 - Over time, estrangements have a serious emotional impact.
 - They reunited after a two-year estrangement.
 - Reaching a trade agreement is a tough prospect in light of the two nations' long-standing estrangement.
 - Many people feel a sense of estrangement from both main political parties.